WCM Proteomics and Metabolomics Core Facility

 

News

  • Jul 2018 Completion of the 300th service project!
  • Jul 2018 Price list is updated for fiscal year 2019. New prices will take effect after July 4th, 2018.
  • Jan 2018 PNAS paper published with Dr. Lewis Cantley "Fenofibrate prevents skeletal muscle loss in mice with lung cancer" (http://www.pnas.org/content/115/4/E743)
  • Jan 2018 New service released: Full panel tracing of C13 labeled polar metabolites.
  • May 2017 New service released: targeted polar metabolite profiling. 

 

Overview of Services

Established in 2016, the Weill Cornell Medicine (WCM) Meyer Cancer Center Proteomics and Metabolomics Core Facility provides mass spectrometry based analysis of proteins, peptides, metabolites and other biochemical molecules.

The core facility is open to Weill Cornell Medicine users as well as external users from academic institutions and commercial enterprises.

 

Services

  • Proteomics
    • Protein Identification
    • Protein Quantitation
      • Methods include: SILAC, TMT, Label-free, spiked standards, etc.
    • Post-Translational Modification (PTM)
      • Phosphorylation, ubiquitination, acetylation, N/C-term processing, etc.
  • Metabolomics
    • Targeted profiling of polar metabolites (Targeted detection of metabolites in a predefined panel, which includes many central metabolites. See the list HERE.)
    • Stable isotope tracing for polar metabolites (e.g. C13 glucose labeling)
      • Type 1: Tracing of selected metabolites (Up to 10 metabolite isotopologues from the panel can be specified. Please specify the metabolites and number of C13 using this TEMPLATE.)
      • Type 2: Full panel tracing (Exhaustive tracing of all detected metabolites. No need to know beforehand if a particular metabolite is labeled or not.) 
    • New method development (Usually user needs to provide standard compounds)

Fees

 

Click HERE to see pricing

 

Sample submission

 

Please follow instructions in "Links and Resources" section below. An iLab account is needed to request services.

 

 

     

Instrumentation

  • Orbitrap Fusion Lumos
  • Orbitrap Q Exactive 
  • Vanquish UPLC
  • Easy-nLC 1200 UPLC 
  • Easy-nLC 1000 UPLC 

Publications

list of publications on Pubmed

Links and Resources

Contact us

Director

Guoan Zhang PhD
guz2004@med.cornell.edu
(646) 962-6222

 

Core Staff

Taojunfeng Su - tas2033@med.cornell.edu
(646) 962-9739

 

Mengmeng Zhu - mez2005@med.cornell.edu
(646) 962-9739

 

Location/Shipping Address

413 East 69th Street, BRB 1552 (Zhang lab)
New York, NY 10021
Lab phone: 646-962-9739


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