WCM Proteomics and Metabolomics Core Facility

News

Nov 2018 New service released: Targeted polyamines analysis.
Sep 2018 New service released: Targeted Thyroid hormones (T3/T4) analysis.
Jul 2018 Completion of the 300th service project!
More News ...

Overview of Services

Established in 2016, the Weill Cornell Medicine (WCM) Meyer Cancer Center Proteomics and Metabolomics Core Facility provides mass spectrometry based analysis of proteins, peptides, metabolites and other biochemical molecules. The core facility is open to Weill Cornell Medicine users as well as external users from academic institutions and commercial enterprises.

Services

Proteomics

Protein Identification
Protein Quantitation
- Methods include: SILAC, TMT, Label-free, spiked standards, etc.
Post-Translational Modification (PTM)
- Phosphorylation, ubiquitination, acetylation, N/C-term processing, etc.

Metabolomics

Targeted profiling of polar metabolites (Targeted detection of metabolites in a predefined panel, which includes many central metabolites such as glycolysis/TCA intermediates and amino acids. See the list HERE.)
Stable isotope tracing / flux for polar metabolites (e.g. C13 glucose labeling)

Type 1: Tracing of selected metabolites (Up to 10 metabolites from the panel can be specified. Please use compound names from the LIST to avoid ambiguity.)
Type 2: Full panel tracing (Exhaustive tracing of all detected metabolites. No need to know beforehand if a particular metabolite is labeled or not.)

New! Thyroid hormones triiodothyronine/thyroxine (T3/T4) absolute quantitation (100 ul serum is needed)
New! Targeted analysis of 7 polyamines (See the list HERE.)
New method development