ALERT

In observance of U.S. holiday, Independence Day, the U.S. iLab Operations Software offices will be closed on Monday, July 3rd and Tuesday, July 4th. We will have support for EU and APAC on those dates during business hours. We will resume normal U.S. support hours on Wednesday, July 5th.  For urgent matters, please add "Urgent" to the ticket subject and we will prioritize those requests first.

 

Thank You!

WCM CLC Proteomics and Metabolomics Core Facility

News

May 2017 New metabolomics services are available. We start to take metabolomics samples.

2017-01-14 Billing for Tri-Institutional Therapeutics Discovery Institute  (TDI) users through iLAB has been streamlined. Journal voucher processing will not be needed in the future.

2017-01-10 Discount available for Metabolon metabolomics measurements for Weill Cornell users through WCM Qatar until June 30, 2017. See details HERE.

Overview of Service

Established in 2016, the Weill Cornell Medicine (WCM) Core Laboratories Cener (CLC) Proteomics and Metabolomics Core Facility provides mass spectrometry based analysis of proteins, peptides, metabolites and other biochemical molecules.

The resources and services of the core facility are open to all investigators at Weill Cornell Medicine, Cornell University and Cornell-affiliated institutions.  The facility also provides services to external investigators at both academic institutions and commercial enterprises.

Services

  • Proteomics
    • Protein Identification: ID of proteins from SDS-PAGE and of proteins in-solution. 
    • Protein Quantitation: Label-free (intensity based / spectral counting); stable isotope labeling by amino acids in cell culture (SILAC); tandem mass tags (TMT); spiked standards. 
    • Post-Translational Modification Analysis: Phosphorylation; ubiquitination; acetylation; N-term / C-term processing; other PTMs. 
    • MS Data Analysis: Database searching; statistical analysis for quantitation.
  • Metabolomics
    • targeted profiling of polar metabolites. See the list HERE. 
    • Stable isotope tracing
    • Absolute quantitation

 

Instrumentation

  • Orbitrap Fusion Lumos 
  • Orbitrap Q Exactive 
  • Vanquish UPLC
  • Easy-nLC 1200 UPLC 
  • Easy-nLC 1000 UPLC 

Publications

list of publications on Pubmed

Contact us

Director

Guoan Zhang PhD
guz2004@med.cornell.edu
(646) 962-6222

 

Core Staff

Zhe Cheng - zhc2010@med.cornell.edu
Taojunfeng Su - tas2033@med.cornell.edu
Yimeng (Lizzy) Zhao - yiz2016@med.cornell.edu
(646) 962-9739

Location

413 East 69th Street, BRB 1552
New York, NY 10021
Lab phone: 646-962-9739

Links and Resources

  1. Service fees.
  2. iLab instructions for External users, Internal users and PIs.
  3. For payment instructions, please click HERE.
  4. For proteomics sample preparation guide lines, please click HERE.
  5. To view the sample preparation protocol for the targeted polar metabolites assay, please click HERE.
  6. To view the list of polar metabolites for the targeted LC-MS assay, please click HERE.
  7. Proteomics and metabolomics services offered by the cores of Weill Cornell Medicine-Qatar.